The group of Prof. Vandamme from the division of Clinical and Epidemiological Virology of the Rega Institute is involved in research on the molecular epidemiology of HIV, HCV and HTLV viruses, and on HIV drug resistance in clinical context. The laboratory performs HIV drug resistance tests for the AIDS Reference Laboratory in Leuven.

The lab of Prof. Vandamme has developed a widely used freely available genotypic HIV-1 drug resistance interpretation tool: the REGA algorithm (currently V6.4.01), which tries to predict treatment response in HIV patients based on HIV genotypic data.

More recently, the group has been involved in the development of software that automatically determines a subtype, the freely available Rega HIV-1 subtyping tool (V2.0)

Katholieke Universiteit Leuven, REGA Institute, Laboratory for Clinical and Epidemiological Virology, Belgium.
WWW: http://www.kuleuven.ac.be/rega/